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HelpTest Code ACHRAM Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Additional Codes
| Mayo | ARBI |
| Epic ID | LAB836 |
Specimen Type
SerumOrdering Guidance
Standalone testing (this test) is recommended in certain situations.
This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held for 1 week and assayed if sufficiently decayed or canceled if radioactivity remains.
Specimen Required
Patient Preparation: For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication.
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Serum must be separated from cells within 2 hours of collection and poured off.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 72 hours |
Transport refrigerated.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Radioimmunoassay (RIA)
Testing Algorithm
This is the primary diagnostic test for myasthenia gravis.
Useful For
Supporting the diagnosis of autoimmune myasthenia gravis (MG) in adults and children
Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders
An adjunct to the test for P/Q-type calcium channel binding antibodies as a diagnostic aid for Lambert-Eaton myasthenic syndrome
Day(s) Performed
Monday through Sunday
Report Available
3 to 6 daysReference Values
≤0.02 nmol/L
CPT Code Information
86041