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HelpTest Code ACMFSM Acetylcholine Receptor Modulating Antibody, Flow Cytometry Assay, Serum
Additional Codes
| Mayo | ACMFS |
| Epic ID | LAB3316 |
Specimen Type
SerumOrdering Guidance
Typically, physicians will order acetylcholine receptor (AChR) binding, blocking, and modulating antibodies. Mayo Clinic Laboratories' (MCL) tests are not named in that manner; instead these are offered as myasthenia gravis (MG) evaluations. MGMR / Myasthenia Gravis Evaluation with Muscle-Specific Kinase (MuSK) Reflex, Serum is the testing of choice in most cases.
AChR blocking antibody testing is no longer offered individually as it offers no added-value to the diagnosis and management of MG.
Specimen Required
Only orderable as part of a profile. For more information see:
MGLE / Myasthenia Gravis/Lambert-Eaton Myasthenic Syndrome Evaluation, Serum
MGMR / Myasthenia Gravis Evaluation with Muscle-Specific Kinase (MuSK) Reflex, Serum
PAVAL / Paraneoplastic, Autoantibody Evaluation, Serum
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 72 hours |
Transport refrigerated.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Only orderable as part of a profile. For more information see:
MGLE / Myasthenia Gravis/Lambert-Eaton Myasthenic Syndrome Evaluation, Serum
MGMR / Myasthenia Gravis Evaluation with Muscle-Specific Kinase (MuSK) Reflex, Serum
PAVAL / Paraneoplastic, Autoantibody Evaluation, Serum
Flow Cytometry
Useful For
Diagnosis for autoimmune myasthenia gravis (MG) in adults and children
Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders.
This test is a qualitative assay and should not be used for monitoring purposes.
Day(s) Performed
Monday, Wednesday, Saturday
Report Available
5 to 8 daysReference Values
Only orderable as part of a profile. For more information see:
MGLE / Myasthenia Gravis/Lambert-Eaton Myasthenic Syndrome Evaluation, Serum
MGMR / Myasthenia Gravis Evaluation with Muscle-Specific Kinase (MuSK) Reflex, Serum
PAVAL / Paraneoplastic, Autoantibody Evaluation, Serum
Negative
CPT Code Information
86043