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Test Code AMIODM Amiodarone, Serum

Additional Codes

Mayo AMIO
Epic ID LAB567

 

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions:

1. Draw blood no sooner than 12 hours (trough value) after last dose or immediately before next scheduled dose.

2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  24 hours
UPH Waterloo Region Lab Test Catalog Note:

Transport refrigerated.

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Liquid Chromatography Mass Spectrometry (LC-MS/MS)

Useful For

Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact

 

Evaluating possible amiodarone toxicity

 

Assessing patient compliance

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Reference Values

AMIODARONE

Trough Value

0.5-2.0 mcg/mL: Therapeutic concentration

>2.5 mcg/mL: Toxic concentration

 

DESETHYLAMIODARONE

No therapeutic range established for desethylamiodarone; activity and serum concentration are similar to parent drug.

CPT Code Information

80151