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HelpTest Code BCGRM Immunoglobulin Gene Rearrangement, Blood
Additional Codes
| Mayo | BCGR |
| Epic ID | LAB4988 |
Special Instructions
Specimen Type
Whole bloodShipping Instructions
Specimen must arrive within 7 days of collection.
Specimen Required
Container/Tube:
Preferred: Lavender top (EDTA)
Acceptable: Yellow top (ACD)
Specimen Volume: 4 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Ambient (preferred) | 7 days |
| Refrigerated | 7 days |
Transport EDTA whole blood at room temperature in original tube.
Reject Due To
| Gross hemolysis | Reject |
| Moderately to severely clotted | Reject |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Polymerase Chain Reaction (PCR)
Useful For
Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using whole blood specimens
Identifying neoplastic cells as having B-cell or plasma cell differentiation
Monitoring for a persistent neoplasm by detecting an immunoglobulin gene rearrangement profile similar to one from a previous neoplastic specimen
Day(s) Performed
Monday through Friday
Reference Values
An interpretive report will be provided.
CPT Code Information
81261-IGH (Immunoglobulin heavy chain locus) (eg, leukemias and lymphomas B-cell), gene rearrangement analysis to detect abnormal clonal populations; amplified methodology (eg. polymerase chain reaction)
81264-IGK (Immunoglobulin kappa light chain locus) (eg, leukemia and lymphoma, B-cell) gene rearrangement analysis, evaluation to detect abnormal clonal populations