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HelpTest Code C2AD2M PrecivityAD2, Plasma
Additional Codes
| Mayo | C2AD2 |
| Epic ID | LAB5799 |
Specimen Type
PlasmaOrdering Guidance
This blood test is intended for use in patients aged 50 and older with signs or symptoms of mild cognitive impairment or dementia who are undergoing evaluation for Alzheimer disease or other forms of cognitive decline.
Shipping Instructions
1. Specimens must be shipped frozen on dry ice.
2. Place labeled aliquot tubes inside a larger tube or vial for transport.
Specimen Required
Supplies: Screw cap micro tube, 2 mL, PCR Performance Tested, Low protein-binding (T983)
Collection Container/Tube: 10 mL Purple top (K EDTA)
Submission Container/Tube: Two 2-mL screw cap micro tubes
Specimen Volume: 3 mL in 2 tubes, each containing 1.5 mL
Collection Instructions:
1. Centrifuge within two hours of collection.
2. Label two 2-mL screw-cap micro tubes.
3. Aliquot 1.5 mL of plasma into each labeled micro tube.
4. Freeze plasma (no longer than 2 hours after collection) at or below -20° C.
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma | Frozen | |
Transport frozen.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Outside of age range Specimen collected outside of testing range (too long in storage before arrival to testing facility) Insufficient volume Incorrect labeling |
Reject |
Performing Laboratory
C2N Diagnostics LLCMethod Name
Immunoprecipitation/Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Useful For
Assisting in the evaluation of adult patients, aged 50 years and older, with signs or symptoms of mild cognitive impairment or dementia who are being assessed for Alzheimer disease and other causes of cognitive decline
This is not intended for patients younger than 50 years, or for use as a screening test in patients without signs or symptoms of cognitive impairment, or for serial testing for assessment of longitudinal changes.
Day(s) Performed
Monday through Friday
Report Available
13 days post sample receipt from MCLReference Values
Amyloid Probability Score 2 (APS2) (range of 0-100):
Negative: 0-47
Positive: 48-100
Abeta42/40 Ratio:
≥0.095 Consistent with absence of amyloid plaques
Percent p-tau217:
<4.2% consistent with absence of brain amyloid plaques
CPT Code Information
0503U