Test Code CAGGM Cold Agglutinin Titer, Serum
Additional Codes
| Mayo | CATTR |
| Epic ID | LAB849 |
Specimen Type
Serum RedOrdering Guidance
The cold agglutinin test is not specific for Mycoplasma pneumoniae and is not recommended to diagnose M pneumoniae infections. To diagnose M pneumoniae infections, order MPRP / Mycoplasma (Mycoplasmoides) pneumoniae with Macrolide Resistance Reflex, Molecular Detection, PCR, Varies. For screening recent or past exposure to M pneumoniae, order MYCO / Mycoplasma pneumoniae Antibodies, IgG and IgM, Serum.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 4 mL
Pediatric Volume: 1 mL
Collections Instructions:
1. Use a warm pack to keep specimen at 37° C prior to and after collecting.
2. Allow specimen to clot at 37° C.
3. Centrifuge at 37° C and aliquot serum into plastic vial immediately after blood clots or within one hour of collection.
4. Do not refrigerate prior to separation of serum from red cells.
Must be collected in serum red top NO GEL tube and allowed to clot at 37oC (USE A WARM PACK).
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 7 days |
| Frozen | 7 days | |
| Ambient | 72 hours |
Transport refrigerated.
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Titration/Red Cell Agglutination
Useful For
Detection of cold agglutinins in patients with suspected cold agglutinin disease
This test is not recommended to diagnose Mycoplasma pneumoniae infections.
Day(s) Performed
Monday through Friday, Sunday
Report Available
1 to 3 daysReference Values
Titer results:
>64: Elevated
>1000: May be indicative of hemolytic anemia
CPT Code Information
86157