Test Code EPOIM Erythropoietin, Serum
Additional Codes
| Mayo | EPO |
| Epic ID | LAB873 |
Special Instructions
Specimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL serum
Collection Instructions:
1. Morning collection, 7:30 a.m. to 12 p.m. is preferred due to diurnal variation. For more information see Cautions.
2. Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 14 days | |
| Ambient | 7 days |
Transport refrigerated.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross Icterus | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Immunoenzymatic Assay
Testing Algorithm
The following algorithms are available:
-Erythrocytosis Evaluation Testing Algorithm
-Myeloproliferative Neoplasm: A Diagnostic Approach to Bone Marrow Evaluation
-Myeloproliferative Neoplasm: A Diagnostic Approach to Peripheral Blood Evaluation
Useful For
An aid in distinguishing between primary and secondary polycythemia
Differentiating between appropriate secondary polycythemia (eg, high-altitude living, pulmonary disease, tobacco use) and inappropriate secondary polycythemia (eg, tumors)
Identifying candidates for erythropoietin (EPO) replacement therapy (eg, those with chronic kidney disease)
Evaluating patients undergoing EPO replacement therapy who demonstrate an inadequate hematopoietic response
Day(s) Performed
Monday through Friday
Report Available
1 to 3 daysReference Values
2.6-18.5 mIU/mL
CPT Code Information
82668