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HelpTest Code G6PDM Glucose 6-Phosphate Dehydrogenase Enzyme Activity, Blood
Additional Codes
| Mayo | G6PD1 |
| Epic ID | LAB571 |
Special Instructions
- Newborn Screening Act Sheet Glucose-6-Phosphate Dehydrogenase Deficiency
- Newborn Screen Follow-up for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
- Glucose-6-Phosphate Dehydrogenase (G6PD) Genotyping Interpretive Algorithm
- Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Diagnostic Algorithm
Specimen Type
Whole Blood ACD-BPlease use EDTA.
Specimen Required
Collection Container/Tube:
Preferred: Yellow top (ACD solution B)
Acceptable: Lavender top (EDTA) or yellow top (ACD solution A)
Specimen Volume: 6 mL
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood ACD-B | Refrigerated | 20 days |
Transport refrigerated.
Reject Due To
| Gross hemolysis | Reject |
| Fully clotted | Reject |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Kinetic Spectrophotometry
Testing Algorithm
The following are available:
-Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Diagnostic Algorithm
-Glucose-6-Phosphate Dehydrogenase (G6PD) Genotyping Interpretive Algorithm
-Newborn Screen Follow-up for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency
-Newborn Screening Act Sheet Glucose-6-Phosphate Dehydrogenase Deficiency
Useful For
Evaluation of individuals with episodic or chronic Coombs-negative non-spherocytic hemolytic anemia
Rapid testing to assess glucose 6-phosphate dehydrogenase (G6PD) enzyme capacity prior to rasburicase or other therapies that may cause hemolysis or methemoglobinemia in G6PD deficient patients
May aid in the creation of a comprehensive patient profile and can ensure appropriate patient monitoring for developing anemia
Day(s) Performed
Monday through Friday
Report Available
1 to 4 daysReference Values
≥12 months of age: 8.0-11.9 U/g Hb
Reference values have not been established for patients younger than 12 months.
CPT Code Information
82955