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Test Code HMU24M Heavy Metals Screen, with Reflex, 24 Hour, Urine

Additional Codes

Mayo HMU24
Epic ID LAB398

 

Specimen Type

Urine


Specimen Required


1. For the 48-hour period prior to the start of collection, as well as during the collection, patient should not eat seafood.

2. High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic aliquot container with no metal cap or glued insert

Submission Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 6 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Refrigerate specimen within 4 hours of completion of 24-hour collection.

3. See Metals Analysis Specimen Collection and Transport for complete instructions.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


UPH Waterloo Region Lab Test Catalog Note:

Refrigerate during and after collection for the 24 hour urine sample.  

Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  7 days
UPH Waterloo Region Lab Test Catalog Note:

Transport 6 mL of 24 hour urine refrigerated. 

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)

Profile Information

Test ID Reporting Name Available Separately Always Performed
ASHU Arsenic, 24 Hr, U Yes, (order ASU24) Yes
CDHMU Cadmium, 24 Hr, U Yes, (order CDU) Yes
HGHU Mercury, 24 Hr, U Yes, (order HGU) Yes
PBHU Lead, 24 Hr, U Yes, (order PBU) Yes

Testing Algorithm

If arsenic concentration is greater than or equal to 10 mcg/L, then speciation will be performed at an additional charge.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
SPASU Arsenic Speciation, 24 Hr, U Yes No

Useful For

Detecting arsenic, cadmium, mercury, and lead exposure and toxicity using 24-hour urine specimens

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days

Reference Values

ARSENIC:

0-17 years: Not established

≥18 years: <35 mcg/24 h

 

CADMIUM:

0-17 years: Not established

≥18 years: <0.7mcg/24 h

 

MERCURY:

0-17 years: Not established

≥18 years: <2 mcg/24 h

Toxic concentration: >50 mcg/24 h

 

The concentration at which toxicity is expressed is widely variable between patients. The lowest concentration at which toxicity is usually apparent Is 50 mcg/24 h.

 

LEAD:

0-17 years: Not established

≥18 years: <2 mcg/24 h

CPT Code Information

82175

82300

83825

83655