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Test Code ITRMM Itraconazole, Serum

Additional Codes

Mayo ITCON
Epic ID LAB2567

 

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top (serum gel/SST are not acceptable)

Acceptable: None

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.18 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 29 days
  Ambient  29 days
  Frozen  29 days
UPH Waterloo Region Lab Test Catalog Note:

Transport refrigerated.

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Useful For

Verifying systemic absorption of orally administered itraconazole

 

Patients with life-threatening fungal infections

 

Patients considered at risk for poor absorption or rapid clearance of itraconazole

Day(s) Performed

Monday through Friday; Saturday

Report Available

1 to 3 days

Reference Values

ITRACONAZOLE (TROUGH):

>0.5 mcg/mL (localized infection)

>1 mcg/mL (systemic infection)

 

HYDROXYITRACONAZOLE:

Hydroxyitraconazole is an active metabolite; no defined therapeutic range has been established.

CPT Code Information

80189