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HelpTest Code LAMOTM Lamotrigine, Serum
Additional Codes
| Mayo | LAMO |
| Epic ID | LAB475 |
Specimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Collect blood immediately before next scheduled dose.
2. Only for sustained-release formulations, collect blood a minimum of 12 hours after last dose.
3. Within 2 hours of collection, centrifuge.
4. For red-top tubes, immediately aliquot serum into a plastic vial.
5. For serum gel tubes, the serum must be aliquoted into a plastic vial within 24 hours of collection.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Transport refrigerated.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful For
Monitoring serum concentration of lamotrigine
Assessing compliance
Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs that interact pharmacokinetically with lamotrigine
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 2 daysReference Values
Patients receiving therapeutic doses usually have lamotrigine concentrations of 3.0-15.0 mcg/mL.
CPT Code Information
80175