Useful For

Screen for the following congenital metabolic disorders: 1) T4: Neonatal hypothyroidism. 2) Galactosemia: Inability to metabolize galactose resulting in failure to thrive on milk. 3 Hemoglobinopathies: Diseases that affect the kind of hemoglobin or the amount of hemoglobin in red blood cells. These include Hemoglobin E, C, D, and S. 4)Congenital Adrenal Hyperplasia: Enzyme deficiency that prevents the production of the stress hormone cortisol and a salt retaining hormone aldosterone and increases the production of a male hormone androgen. Life threatening vomiting and severe dehydration may develop. 5)Expanded Screening Disorders: A.Amino Acid Disorders: Inability to break down specific proteins into amino acids. B.Fatty Acid Oxidative Disorders: Inability to break down stored fats into energy. C.Organic Acid Disorders: Chemical imbalance in which fats, sugars or proteins are not broken down properly, causing toxicity. 6)Biotinidase Deficiency: Deficiency results in improper functioning of several enzymes, leading to irreversible neurological damage. 7) Cytstic Fibrosis: Inherited disorder which causes lung infections and digestive problems with malnutrition