Test Code NMOCS Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Serum
Additional Codes
| Mayo | NMOFS |
| Epic ID | LAB4249 |
Specimen Type
SerumOrdering Guidance
Specimen Required
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Frozen | 28 days | |
| Ambient | 72 hours |
Transport refrigerated.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Flow Cytometry
Testing Algorithm
When the results of this assay require further evaluation, NMOTS / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Titer Assay, Serum will be performed at an additional charge.
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| NMOTS | NMO/AQP4 FACS Titer, S | No | No |
Useful For
Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD)
Diagnosis of autoimmune AQP4 channelopathy
Diagnosis of neuromyelitis optica (NMO)
Distinguishing NMOSD from multiple sclerosis early in the course of disease
Day(s) Performed
Monday, Tuesday, Thursday
Report Available
5 to 8 daysReference Values
Negative
CPT Code Information
86053
86053-titer (if appropriate)