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Test Code NSESFM Neuron-Specific Enolase (NSE), Spinal Fluid

Additional Codes

Mayo NSESF
Epic ID LAB4278

 

Specimen Type

CSF


Specimen Required


Container/Tube: Sterile vial

Specimen Volume: 0.5 mL


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 15 days
  Ambient  72 hours
UPH Waterloo Region Lab Test Catalog Note:

Transport refrigerated.

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Homogeneous Time-Resolved Fluorescence

Useful For

An auxiliary test in the diagnosis of Creutzfeldt-Jakob disease

 

An auxiliary test in the diagnosis of small cell lung carcinoma metastasis to central nervous system or leptomeninges

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Reference Values

Normal: ≤15 ng/mL

 

Indeterminate: 15-30 ng/mL

 

Elevated: >30 ng/mL

Elevated results may indicate the need for additional workup. Possible causes may be neuron-specific enolase-secreting central nervous system/leptomeningeal tumor or rapid neuronal destruction from a variety of causes. In the context of dementia, elevated results may be suggestive of Creutzfeldt-Jakob disease.

CPT Code Information

83520