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HelpTest Code PLA2IM Phospholipase A2 Receptor, Immunofluorescence, Serum
Additional Codes
| Mayo | PLA2I |
| Epic ID | LAB4956 |
Specimen Type
SerumOrdering Guidance
This test can be used in a complementary fashion with a quantitative enzyme-linked immunosorbent assay to confirm a positive result, especially if it is a low-level titer. Since the immunofluorescence is more sensitive, it can also be used to detect or follow patients with low level antibodies not detected by ELISA.
Specimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 14 days | |
| Ambient | 8 hours |
Transport refrigerated.
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Indirect Immunofluorescence Assay (IFA)
Useful For
Distinguishing primary from secondary membranous nephropathy in patients with low levels of anti-phospholipase A2 receptor (PLA2R) antibodies
Screening for anti-PLA2R antibodies
Monitoring patients with membranous nephropathy at very low antibody titers
Day(s) Performed
Monday, Wednesday, Friday
Report Available
3 to 7 daysReference Values
Negative
CPT Code Information
86255