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HelpTest Code PPAPM Parental Sample Prep for Prenatal Microarray Testing, Blood
Additional Codes
| Mayo | PPAP |
| Epic ID | LAB86031 |
Specimen Type
Whole bloodAdditional Testing Requirements
This test must be ordered in conjunction with CMAP / Chromosomal Microarray, Prenatal, Amniotic Fluid/Chorionic Villus Sampling; CMAPC / Chromosomal Microarray, Autopsy, Products of Conception, or Stillbirth, Varies; or CMAMT / Chromosomal Microarray, Autopsy/Products of Conception/Stillbirth, Tissue. Each parent should have a specimen collected for this test ID using a different order number than the fetal specimen collected for the CMAP, CMAPC, or CMAMT order.
Necessary Information
1. The reason for testing is required.
2. Include the name listed on the prenatal specimen that was submitted for CMAP / Chromosomal Microarray, Prenatal, Amniotic Fluid/Chorionic Villus Sampling; CMAPC / Chromosomal Microarray, Autopsy, Products of Conception, or Stillbirth, Varies; or CMAMT / Chromosomal Microarray, Autopsy/Products of Conception/Stillbirth, Tissue.
Specimen Required
This test requires 2 blood specimens: 1 sodium heparin and 1 EDTA
Specimen Type: Whole blood
Container/Tube: Green top (sodium heparin) and lavender top (EDTA)
Specimen Volume: 3 mL EDTA and 4 mL sodium heparin
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimens in original tubes. Do not aliquot.
Specimen Minimum Volume
2 mL EDTA and 2 mL sodium heparin whole blood
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Ambient (preferred) | |
| Refrigerated | ||
Transport at room temperature.
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Performing Laboratory
Mayo Clinic Laboratories in Rochester
Testing Algorithm
This test contains no charge and serves as a way to correlate proband and parental specimens. If additional testing is warranted, the appropriate tests will be added.
When CMAP / Chromosomal Microarray, Prenatal, Amniotic Fluid/Chorionic Villus Sampling; CMAPC / Chromosomal Microarray, Autopsy, Products of Conception, or Stillbirth; or CMAMT / Chromosomal Microarray, Autopsy/Products of Conception/Stillbirth, Tissue is ordered, parental blood specimens are collected and prepared for confirmation studies should an abnormality be detected on the prenatal sample. If an abnormality is detected on the fetal specimen, the most appropriate testing (microarray, fluorescence in situ hybridization, or chromosome analysis) to aid in the interpretation of the prenatal result can be performed on the parental specimens. A paternal blood specimen is requested but not required. Maternal cell contamination testing will be performed on the maternal blood and prenatal specimens to rule out the presence of maternal cells in the fetal sample.
If this test is ordered in conjunction with a molecular test and no other cytogenetics testing is ordered, the test will be changed to MATCC / Maternal Cell Contamination, Molecular Analysis, Varies. If both CMAP / Chromosomal Microarray, Prenatal, Amniotic Fluid/Chorionic Villus Sampling or CMAPC / Chromosomal Microarray, Autopsy, Products of Conception, or Stillbirth, and other molecular testing is ordered, MATCC will be added, per laboratory protocol.
Useful For
Preparing parental blood specimen for possible confirmation testing if an abnormality is detected on the prenatal array sample
DNA extraction of the maternal blood specimen used for maternal cell contamination testing
Day(s) Performed
Monday through Friday
Report Available
VariesReference Values
An interpretive report will be provided.
CPT Code Information
This test ID contains no charge and serves as a way to correlate proband parental specimens. If additional testing is warranted, the appropriate tests will be added.