Test Code PPFEM Protoporphyrins, Fractionation, Whole Blood
Additional Codes
| Mayo | PPFE |
| Epic ID | LAB5282 |
Special Instructions
Specimen Type
Whole bloodOrdering Guidance
This test is for assessment for protoporphyria., and erythropoietic porphyria The preferred test for lead toxicity in children is blood lead. For more information see PBDV / Lead, Venous with Demographics, Blood or PBDC / Lead, Capillary, with Demographics, Blood.
The preferred test for the assessment of occupational exposure to lead is PBPFD / Lead Profile Occupational Exposure, Blood.
For suspected hepatic porphyria, the preferred screening test is urine porphyrins. For more information, see PQNRU / Porphyrins, Quantitative, Random, Urine.
Necessary Information
Include a list of medications the patient is currently taking.
Specimen Required
Patient Preparation: Patient must not consume any alcohol for 24 hours before specimen collection.
Container/Tube:
Preferred: Green top (sodium heparin)
Acceptable: Lavender top (EDTA), dark blue top (metal free heparin), royal blue top (metal free EDTA), green top (lithium heparin)
Specimen Volume: 4 mL
Collection Instructions: Refrigerate specimen as soon as possible.
Specimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Refrigerated | 7 days |
Transport whole blood refrigerated.
Reject Due To
| Gross hemolysis | Reject |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
High-Performance Liquid Chromatography (HPLC) with Fluorescence Detection
Testing Algorithm
This test should not be ordered in conjunction with PEE / Porphyrins Evaluation, Whole Blood.
The following information is available:
-Porphyria (Acute) Testing Algorithm
Useful For
Evaluating patients with possible diagnoses of erythropoietic protoporphyria or X-linked protoporphyria
Establishing a biochemical diagnosis of erythropoietic protoporphyria or X-linked protoporphyria
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysReference Values
Free Protoporphyrin: <20 mcg/dL
Zinc-Complexed Protoporphyrin: <60 mcg/dL
CPT Code Information
82542