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Test Code PTNFTM Phenytoin, Total and Free, Serum

Additional Codes

Mayo PNTFT
Epic ID LAB176

 

Specimen Type

Serum Red


Specimen Required


Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 7 days
  Frozen  14 days
  Ambient  7 days
UPH Waterloo Region Lab Test Catalog Note:

Transport refrigerated.

Reject Due To

Gross hemolysis Reject

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

PNYF: Membrane Separation/KIMS

PNYA: Kinetic interaction of Microparticles in a Solution (KIMS)

Profile Information

Test ID Reporting Name Available Separately Always Performed
PNYF Phenytoin, Free, S Yes Yes
PNYA Phenytoin, Total, S Yes Yes

Useful For

Monitoring for appropriate therapeutic concentration of both free and total phenytoin: free phenytoin level is the best indicator of adequate therapy in renal failure

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day

Reference Values

Phenytoin, Total

Therapeutic: 10.0-20.0 mcg/mL

Critical value: ≥30.0 mcg/mL

 

Phenytoin, Free

Therapeutic: 1.0-2.0 mcg/mL

Critical value: ≥2.5 mcg/mL

CPT Code Information

Phenytoin, total-80185

Phenytoin, free-80186