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HelpTest Code SPG23M Streptococcus pneumoniae IgG Antibodies, 23 Serotypes, Serum
Additional Codes
| Mayo | PN23M |
| Epic ID | LAB2723 |
Specimen Type
SerumOrdering Guidance
This test is the preferred test for patients previously tested for Streptococcus pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment).
The preferred test for patients being evaluated for possible immunodeficiency or for assessment of pneumococcal vaccination response (initial evaluation) is PNTOR / Streptococcus pneumoniae IgG Antibodies, Total, with Reflex, Serum
The preferred test for patients previously tested for total Streptococcus pneumoniae antibodies (as part of follow up testing or part of pre/post vaccine assessment) is PNTO / Streptococcus pneumoniae IgG Antibodies, Total, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL Serum
Collection Instructions: Centrifuge and aliquot serum into plastic vial
Specimen Minimum Volume
Serum: 0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Transport refrigerated.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Bead-Based Multiplex Immunoassay
Useful For
Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines
Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines
Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies
Day(s) Performed
Monday through Friday
Report Available
4 to 6 daysReference Values
Results are reported in mcg/mL
|
Serotype |
Normal value |
|
1 (1) |
≥1.0 |
|
2 (2) |
≥1.0 |
|
3 (3) |
≥1.0 |
|
4 (4) |
≥1.0 |
|
5 (5) |
≥1.0 |
|
8 (8) |
≥1.0 |
|
9N (9) |
≥1.0 |
|
12F (12) |
≥1.0 |
|
14 (14) |
≥1.0 |
|
17F (17) |
≥1.0 |
|
19F (19) |
≥1.0 |
|
20 (20) |
≥1.0 |
|
22F (22) |
≥1.0 |
|
23F (23) |
≥1.0 |
|
6B (26) |
≥1.0 |
|
10A (34) |
≥1.0 |
|
11A (43) |
≥1.0 |
|
7F (51) |
≥1.0 |
|
15B (54) |
≥1.0 |
|
18C (56) |
≥1.0 |
|
19A (57) |
≥1.0 |
|
9V (68) |
≥1.0 |
|
33F (70) |
≥1.0 |
CPT Code Information
86581