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HelpTest Code TGMSM Thyroglobulin Mass Spectrometry, Serum
Additional Codes
| Mayo | TGMS |
| Epic ID | LAB1864 |
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.25 mL Serum
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
Serum: 0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 7 days |
| Frozen | 416 days | |
| Ambient | 72 hours |
Transport refrigerated.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Tryptic Protein Fragmentation, purified with Immunocapture, Analysis by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Testing is performed pursuant to an agreement with SISCAPA Assay Technologies Inc. covering US Patent 7,632,686.
Useful For
Accurate measurement of serum thyroglobulin (Tg) in patients with known or suspected antithyroglobulin autoantibodies (TgAb) or heterophile antibodies (HAb)
Reflex testing of samples with previously unknown TgAb status that prove TgAb positive during immunoassay testing
Assisting in the differential diagnosis of early phase silent thyroiditis versus Graves disease in patients without thyroid cancer (the mass spectrometry-based method would only be required if these patients have TgAb or HAb)
Day(s) Performed
Monday through Friday
Report Available
3 to 10 daysReference Values
Healthy individuals with intact, functioning thyroid: ≤33 ng/mL
CPT Code Information
84432