Ordering Guidance

This test does not quantitate reduced coenzyme Q10 (CoQ10). For reduced CoQ10, order Q10 / Coenzyme Q10, Reduced and Total, Plasma.

The most reliable test for the diagnosis of primary defects in ubiquinone (ie, CoQ10) biosynthesis is direct measurement of CoQ10 in muscle.

Necessary Information

Patient's age is required.

Specimen Required

Patient Preparation:

Fasting: 8 hours, required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Green top (lithium or sodium heparin)

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL plasma

Collection Instructions:

1. Immediately after collection, place specimen on wet ice. Maintain on wet ice until processing.

2. Within 3 hours of collection, centrifuge, aliquot plasma into a plastic vial, and freeze immediately.