Test Code VORI Voriconazole, Serum
Additional Codes
| Mayo | VORI |
| Epic ID | LAB3129 |
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.6 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Transport refrigerated.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Useful For
Monitoring trough levels of voriconazole suggested for:
-Individuals with reduced liver function
-Individuals with cytochrome P450 (CYP) 2C19 alterations associated with poor metabolic function
-Patients taking other medications that affect CYP2C19 activity
-Patients experiencing potential toxicity
Monitoring trough levels in patients who are not responding optimally or have drug interactions that may decrease voriconazole levels or to ensure adequate oral absorption
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 to 2 daysReference Values
1.0-5.5 mcg/mL
Trough level (ie, immediately before next dose) monitoring is recommended.
CPT Code Information
80285