Sign in →

Test Code WAGDRM Alpha Globin Cluster Locus Deletion/Duplication, Blood

Additional Codes

Mayo WAGDR
Epic ID LAB4951

 

Specimen Type

Varies


Ordering Guidance


Sequence variants, other than the alpha T-Saudi and hemoglobin Constant Spring alterations, are not detected by this assay. For detection of single point and other nondeletion variants, order WASEQ / Alpha Globin Gene Sequencing, Varies, if clinically indicated.



Specimen Required


Patient Preparation: A previous bone marrow transplant from an allogeneic donor will interfere with testing. For instructions for testing patients who have received a bone marrow transplant, call 800-533-1710.

 

Specimen Type: Whole blood

Container/Tube:

Preferred: Lavender top (EDTA)

Acceptable: Yellow top (ACD)

Specimen Volume: 3 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send whole blood specimen in original tube. Do not aliquot.


Specimen Minimum Volume

Blood: 1 mL

Specimen Stability Information

Specimen Type Temperature Time
Varies Varies
UPH Waterloo Region Lab Test Catalog Note:

Transport EDTA whole blood refrigerated in original tube.

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Dosage Analysis by Polymerase Chain Reaction (PCR)/Quantitative Polymerase Chain Reaction (qPCR)/Multiplex Ligation-Dependent Probe Amplification (MLPA)

Useful For

Diagnosis of alpha-thalassemia

 

Carrier screening for individuals from high-risk populations for alpha-thalassemia

 

This test is not useful for diagnosis or confirmation of beta-thalassemia or hemoglobinopathies.

Day(s) Performed

Varies

Report Available

9 to 13 days

Reference Values

An interpretive report will be provided.

CPT Code Information

81269